Examples of Projects supported

Some of the following have been successfully completed and conclusions published.

Professor Mark Gravenor and Dr Owen Bodger.    

An Early Response System for mapping and control of Bird Flu.

In this project, researchers at Swansea University's College of Medicine designed a mathematical model to help understand and control the early stages of an outbreak of bird influenza virus in the UK. This practical mathematical model continues to be maintained by Professor Gravenor and his team at the College of Medicine on behalf of UK government (DEFRA) for potential use during any epidemic. 


Professor Mark Gravenor and Dr Owen Bodger.

Prevention of MRSA infection spread in Wales.

This project focuses on the spread of the very important problem of MRSA infections in hospitals in Wales. Professor Gravenor and his team are developing a mathematical model of the spread of this antibiotic resistant MRSA bug, so that more successful methods can be developed for preventing the spread of the bug and the diseases it causes in hospitals.

 

Professor Steve Bain.

Controlling Diabetes.

With the support of Novo Nordisk the All-Wales Diabetes Research Network Laboratory is now in the Institute of Life Science at Swansea's College of Medicine. There, the research of Professor Bain and his team focuses on the very much needed better medical control of diabetes, and stronger prevention of the many fatal complications of the disease.

 

Professor Keith Lloyd.

Mental Health in Wales - Working with industry to advance research trials.

Funding from the MHRN in England is being used to investigate and promote working with industry in mental health research trials. Professor Lloyd and his team working closely with the network in England - with the goal of advancing mental health research methods in Wales.


Dr Ryan Trickett.

Wales Lower Limb Trauma Recovery.

Dr Trickett is developing a novel "scale" method to allow measurement of recovery following severe lower limb injury.

 

Dr Claire Morgan.

Prostate Cancer.

Dr Morgan is investigating underlying biological mechanisms of tumour growth in this very common and important cancer of men. The work aims to lay foundations for novel approaches to treatment and control of this cancer in the future.

 

Professor Ronan Lyons.

Road Traffic Injuries.

Professor Lyons and his team at Swansea's College of Medicine are developing a method for classifying the severity of injuries in road traffic accidents (Injury Severity Classification Study). The aim is to provide a method of practical use to police and ambulance teams dealing with road accident casualties - and one which guides stronger preventive measures in the future.

 

Professor Ronan Lyons.

Obesity in Wales - information from general practitioners.

Professor Lyons and his team are validating information on obesity data from GP records (within the Secure Anonymised information Linkage (SAIL) data bank). The object is to develop health policies for the stronger prevention and treatment of obesity and all its health consequences.                                          

 

Professor Ronan Lyons.

Orthopaedic Service Development.

Professor Lyons and his team are using the Secure Anonymised Information Linkage (SAIL) databank, to develop a method to analyse orthopaedic care pathways. This will support improvements in orthopaedic service design and quality, including the measurement of patient outcomes.

 

Professor Ronan Lyons.

Injury Research.

Professor Lyons is leading research into injury through the International Collaborative Effort on Injury Statistics and Methods (US National Centre Health Statistics). He believes the health burden of injury is underestimated. He utilises all available data and follows up injured individuals - and aims to advance prevention, treatment and rehabilitation of injury.

 

Professor Ronan Lyons.

Dermatology Research.

Skin diseases are important and hence this project is being undertaken on behalf of Public Health Wales NHS Trust. It will use general practice data within the anonymised SAIL databank in order to improve the planning of dermatology services.

 

Professor Ronan Lyons.

“Quit Smoking” Project.

This vital project is being undertaken on behalf of Public Health Wales NHS Trust. The aim to identify the best smoking cessation interventions currently available through general practice and Stop Smoking Wales (SSW). The results will be used to drive advance in "quit smoking" services.

 

Professor Ronan Lyons.

Health Services Access and Public Transport.

This project is being undertaken on behalf of ABM University Health Board as part of NHS Wales modernisation and re-configuration of services. Public transport access is an important issue and Professor Lyons' team are assisting ABMU-HB in developing integrated transport modes for every small area, which may then extend across Wales.

 

Professor Ronan Lyons.

Healthy Cities/Healthy Environment.

This is collaboration between Professor Ronan Lyons’ team at the Farr Institute, Swansea University and Environmental Health Specialists (Swansea City Council). This research programme will use highly detailed specific local data sets for Air, Land, Water, Noise environmental quality and seek to identify whether there are quantifiable effects on local populations. Such information would be tremendously helpful in informing any necessary interventions to protect and improve the health of the public.

 

Dr Ricardo Del Sol.  

The safety of the antimalarial drug, Fexinidazole.

Dr Del Sol and his team aim to resolve whether there are any mutagenic (DNA damaging) effects from Fexinidazole, a promising candidate drug use to treat the very common and important tropical disease, Sleeping Sickness (infection with Trypanosoma brucei).

 

Professor Gareth Jenkins.

Oesophageal Cancer.

Professor Jenkins is investigating the origins of cancer of the gullet (or oesophagus) - and these approaches are highly relevant to future prevention of the disease.

 

Dr Stephen Roberts.

Health Care Outcomes.

This important work investigated measures of senior medical input and outcomes (mortality, readmissions, major infections, lengths of inpatient stay, etc.) for acute emergency admissions across 26 hospitals in England - and will help formulate designs for future services.

  

Professor DRR Williams,

Obesity in the young (Sir Gar Project).

Professor Williams and his team addressed early recognition of obesity in the young in Carmarthenshire (Hywel Dda Trust / Coleg Sir Gar). The study showed that early-life obesity (with a tubby belly) damages the body's metabolism (related to diabetes) and also the body's blood vessels. These important findings emphasise the vital need to prevent obesity early. 

 

Professor Stephen Allen.

International Health: Swansea - West Africa Links.

Professor Allen founded and leads the strong link between Swansea's College of Medicine and ABMU-HB with colleagues in West Africa (in The Gambia, Sierra Leone and Nigeria). These links bring medical staff and students together to work for mutual benefit on health issues of common interest (clinical care, health service delivery, teaching and research). With Gambia there is exchange of medical students plus education and training in diabetes, eye care, clinical audit and pathology. The Ibadan-Swansea Partnership focuses on eLearning.  In Sierra Leone's Ola During Children’s and Princess Christian Maternity Hospitals, nursing practice and laboratory services are being developed.


Professors John White and Stephen Conlan.        

Cancer of the Uterus.

Professors White and Conlan have studied tissue from healthy and cancerous uteri - applying modern molecular and cellular methods in order to recognise signals that characterise the development of cancer in the uterus. These "biomarkers" will be developed as diagnostics and may lay the foundations for novel treatment approaches also.                                                           .

 

Dr G E Johnson. 

Environmental exposures and cancer.

Dr Johnson is looking to improve the use of genetic toxicology (gene damage) information on chemical compounds to which human populations are exposed, and relate this to the risk of developing cancer.

 

 Dr Josie Parker.

 Mycobacterium Tuberculosis Cytochrome P540 in Cholesterol Metabolism: Potential new drug target for latent Mycobacterium Tuberculosis.

This research investigates the utilisation of host cholesterol by TB. This is an essential biological process in latent (dormant) TB infection, for which new drug treatments are desperately needed. This study will further our understanding of this process and examine possible new drug targets.